Increased inflammatory response in aged mice is associated with age-related zinc deficiency and zinc transporter dysregulation.

@article{Wong2013IncreasedIR,
  title={Increased inflammatory response in aged mice is associated with age-related zinc deficiency and zinc transporter dysregulation.},
  author={Carmen P. Wong and Kathy Ruth Magnusson and Emily E. Ho},
  journal={The Journal of nutritional biochemistry},
  year={2013},
  volume={24 1},
  pages={353-9}
}
Aging is a complex process associated with physiological changes in numerous organ systems. In particular, aging of the immune system is characterized by progressive dysregulation of immune responses, resulting in increased susceptibility to infectious diseases, impaired vaccination efficacy and systemic low-grade chronic inflammation. Increasing evidence suggest that intracellular zinc homeostasis, regulated by zinc transporter expression, is critically involved in the signaling and activation… CONTINUE READING
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