Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation.
@article{Takayama2009IncreasedIO, title={Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation.}, author={H. Takayama and K. Nishimura and A. Tsujimura and Y. Nakai and Masashi Nakayama and K. Aozasa and A. Okuyama and N. Nonomura}, journal={The Journal of urology}, year={2009}, volume={181 4}, pages={ 1894-900 } }
PURPOSE
Tumor associated macrophages can regulate the growth of various cancers positively or negatively. Intravesical bacillus Calmette-Guerin instillation is now gold standard treatment for bladder carcinoma in situ. We investigated the correlation between tumor associated macrophages infiltrating bladder carcinoma in situ and the response to intravesical bacillus Calmette-Guerin therapy.
MATERIALS AND METHODS
We examined paraffin embedded tissues from 41 patients with bladder carcinoma in… CONTINUE READING
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