Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene

  title={Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene},
  author={Dietrich Henschler and Spiros Vamvakas and Marga Lammert and Wolfgang Dekant and Bastian Kraus and Brad J. Thomas and K. Ulm},
  journal={Archives of Toxicology},
A retrospective cohort study was carried out in a cardboard factory in Germany to investigate the association between exposure to trichloroethene (TRI) and renal cell cancer. The study group consisted of 169 men who had been exposed to TRI for at least 1 year between 1956 and 1975. The average observation period was 34 years. By the closing day of the study (December 31, 1992) 50 members of the cohort had died, 16 from malignant neoplasms. In 2 out of these 16 cases, kidney cancer was the cause… CONTINUE READING
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Biotransforma - tion of trichloroethene : dose - dependent excretion of 1 , l , l - tri - ehloro - metabolites and mercapturic acids in rats and humans after inhalation

  • U Bemauer, G Bimer, W Dekant, D Henschler
  • Arch Toxicol
  • 1995

A ca ~ - control study of cancer mortality at a transformer - assembly facility

  • F Hunter
  • Int Arch Occup Environ Health
  • 1994

Structures of DNA-adducts normed from haloketenes and halothioketenes: A study to identify possible adducts formed from trichloro- and perchlorocthcne through bioactivation by glutathione conjugation

  • M Miiller, G Birner, D Henschler, W Dekant
  • 1 ARC Scientific Publication Series
  • 1994

Nephrocarcinogenicity of haloalkenes and alkynes

  • S Vamvakas, W Dekant, D Hensehler
  • Renal disposition and nephrotoxicity of…
  • 1993
2 Excerpts

Occupational and lifestyle risk factors for the etiology of renal cell cancer

  • B Schlehofer, C Heuer, D Niehoff, J Wahrendort
  • J Caner Res Clin Oncol
  • 1993

Rish factors for kidney cancer in New South Wales.IV. Occupation

  • M McCredit, JH Stewart
  • Br J Ind Med
  • 1993

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