Increased in vitro tetraploidy: a possible biomarker of non-heritable colorectal cancer?

In vitro tetraploidy (IVT+) in dermal fibroblast monolayer cultures has been studied in a series of patients with non-syndrome colon cancer and a control group to determine its value in identification of genetic predisposition for all colon cancers and its relevance to colon cancer occurrence on the basis of clinical history and pedigree data. Among 41… CONTINUE READING