Increased immunoreactivity of membrane type-1 matrix metalloproteinase (MT1-MMP) and β-catenin in high-risk basal cell carcinoma.

@article{Oh2011IncreasedIO,
  title={Increased immunoreactivity of membrane type-1 matrix metalloproteinase (MT1-MMP) and β-catenin in high-risk basal cell carcinoma.},
  author={Sung Tae Oh and Hyun Seok Kim and Nam Jin Yoo and Won Sin Lee and Baik Kee Cho and Joerg Reichrath},
  journal={The British journal of dermatology},
  year={2011},
  volume={165 6},
  pages={1197-204}
}
BACKGROUND Although various immunohistological markers have been investigated to assess the aggressive characteristics of basal cell carcinoma (BCC), the role of membrane type-1 matrix metalloproteinase (MT1-MMP) has not been well established. OBJECTIVES To clarify the precise role of MT1-MMP in BCC, MT1-MMP expression was studied in various histological subtypes of BCC. MATERIALS AND METHODS High-risk subtypes of BCC were compared by assessing the expression of β-catenin and MT1-MMP. The… CONTINUE READING