Increased hydrogen peroxide in the expired breath of patients with acute hypoxemic respiratory failure.

@article{Sznajder1989IncreasedHP,
  title={Increased hydrogen peroxide in the expired breath of patients with acute hypoxemic respiratory failure.},
  author={Jacob I Sznajder and A Fraiman and Jonathan B Hall and William Sanders and G. Schmidt and G. Crawford and Avi Nahum and Phillip Factor and Laura D Wood},
  journal={Chest},
  year={1989},
  volume={96 3},
  pages={606-12}
}
Acute hypoxemic respiratory failure (AHRF) can result from diverse lung insults. Toxic oxygen metabolites have been implicated in this clinical condition and in animal models of pulmonary edema. Hydrogen peroxide (H2O2), an oxygen metabolite, mediates tissue injury. We measured H2O2 levels by a spectrophotometric technique in the breath condensate of 68 mechanically ventilated patients; 13 patients with normal lungs undergoing elective surgery had no such detectable levels of H2O2. Fifty-five… CONTINUE READING