Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.

@article{George1998IncreasedHI,
  title={Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.},
  author={Donald K. George and Stefano Goldwurm and Graeme A. Macdonald and Lorraine Cowley and Neal I. Walker and Patrick J Ward and Elizabeth C. Jazwinska and Lawrie William Powell},
  journal={Gastroenterology},
  year={1998},
  volume={114 2},
  pages={311-8}
}
BACKGROUND & AIMS Nonalcoholic steatohepatitis (NASH) is a chronic liver disease that occasionally progresses to cirrhosis but usually has a benign course. The aim of this study was to investigate the role of the hemochromatosis mutation Cys282Tyr in development of the mild hepatic iron overload found in some patients with NASH and its association with hepatic damage in these patients. METHODS Fifty-one patients with NASH were studied. The presence of the Cys282Tyr mutation was tested in all… CONTINUE READING
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