Increased hepatic expression of nitric oxide synthase type II in cirrhotic rats.

@article{Wang2004IncreasedHE,
  title={Increased hepatic expression of nitric oxide synthase type II in cirrhotic rats.},
  author={Hai Wang and Xiaoping Chen and Fa-zu Qiu},
  journal={World journal of gastroenterology},
  year={2004},
  volume={10 13},
  pages={1923-7}
}
AIM To determine the role and effect of nitric oxide synthase type II (NOSII) in cirrhotic rats. METHODS Expression of NOSII mRNA was detected by real time RT-PCR. The activity of nitric oxide synthase and serum levels of NO, systemic and portal hemodynamics and degrees of cirrhosis were measured with high sensitive methods. Chinese traditional medicine tetrandrine was used to treat cirrhotic rats and to evaluate the function of NO. Double-blind method was applied during the experiment… CONTINUE READING

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