Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in late pathological stage human prostate cancer

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme best known to many investigators as a ‘housekeeping’ gene used as a loading control on northern blots. Prior studies, however, have shown that GAPDH RNA levels vary greatly among different prostate cancer cell lines. We undertook this study to determine the level of GAPDH gene… (More)