• Psychology, Medicine
  • Published in
    Autism research : official…
    2013
  • DOI:10.1002/aur.1260

Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study.

@article{Brown2013IncreasedGC,
  title={Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study.},
  author={Mark S. Brown and Debra Singel and Susan Hepburn and Donald C Rojas},
  journal={Autism research : official journal of the International Society for Autism Research},
  year={2013},
  volume={6 1},
  pages={
          1-10
        }
}
Increased glutamate levels have been reported in the hippocampal and frontal regions of persons with autism using proton magnetic resonance spectroscopy ((1)H-MRS). Although autism spectrum disorders (ASDs) are highly heritable, MRS studies have not included relatives of persons with ASD. We therefore conducted a study to determine if glutamate levels are elevated in people with autism and parents of children with autism. Single-voxel, point-resolved spectroscopy data were acquired at 3T for… CONTINUE READING

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