Increased glomerular matrix metalloproteinase activity in murine lupus nephritis.

@article{Tveita2008IncreasedGM,
  title={Increased glomerular matrix metalloproteinase activity in murine lupus nephritis.},
  author={Anders Aune Tveita and Ole Petter Rekvig and Svetlana N. Zykova},
  journal={Kidney international},
  year={2008},
  volume={74 9},
  pages={1150-8}
}
Lupus nephritis is associated with thickening of the glomerular basement membrane. Here we measured expression of proteins involved in extracellular matrix turnover in kidneys of lupus-prone mice of the NZBxNZW F1 (B/W) strain before the onset of the disease until the development of proteinuria. Expression of the major isoforms of glomerular basement… CONTINUE READING