Increased gene expression of adrenomedullin and adrenomedullin-receptor complexes, receptor-activity modifying protein (RAMP)2 and calcitonin-receptor-like receptor (CRLR) in the hearts of rats with congestive heart failure.

@article{Totsune2000IncreasedGE,
  title={Increased gene expression of adrenomedullin and adrenomedullin-receptor complexes, receptor-activity modifying protein (RAMP)2 and calcitonin-receptor-like receptor (CRLR) in the hearts of rats with congestive heart failure.},
  author={Kazuhito Totsune and Kazuhiro Takahashi and Harald S Mackenzie and Osamu Murakami and Zenei Arihara and Masahiko Sone and Takashi Mouri and Barry M. Brenner and Sadayoshi Ito},
  journal={Clinical science},
  year={2000},
  volume={99 6},
  pages={541-6}
}
Adrenomedullin is a vasodilator peptide produced in various organs, including heart and kidney. A novel adrenomedullin receptor complex has recently been identified, namely the calcitonin receptor-like receptor (CRLR) and receptor-activity modifying protein (RAMP) 2. In the present study, we have examined gene expression of RAMP2, CRLR and adrenomedullin in hearts and kidneys of rats with congestive heart failure caused by coronary artery ligation. Partial cloning was performed to determine the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

Adrenomedullin in heart failure.

Hypertension research : official journal of the Japanese Society of Hypertension • 2003
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats

E. Øie, L. E. Vinge, +3 authors H. Attramadal
Circulation • 2000

Similar Papers

Loading similar papers…