Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.

@article{Hanemaaijer2000IncreasedGA,
  title={Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.},
  author={Roeland Hanemaaijer and Jan H. Verheijen and Teresa M Maguire and Heiko Visser and Karin H. Toet and E. McDermott and Niall O'higgins and Michael J. Duffy},
  journal={International journal of cancer},
  year={2000},
  volume={86 2},
  pages={
          204-7
        }
}
Matrix metalloproteinases (MMP) types 2 and 9 (also known as gelatinase A and B) are thought to be causally involved in cancer invasion and metastasis. In normal as well as in malignant tissue, both these MMPs occur in multiple forms such as inactive precursors, active enzymes and enzyme-inhibitor complexes. Using newly developed quantitative activity assays, the levels of active MMP-2, total (active and activatable) MMP-2 and total MMP-9 were found to be significantly higher in breast… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 53 CITATIONS

FILTER CITATIONS BY YEAR

2001
2017

CITATION STATISTICS

  • 1 Highly Influenced Citations

  • Averaged 2 Citations per year over the last 3 years

Similar Papers

Loading similar papers…