Increased gastric cancer risk with PTEN IVS4 polymorphism in a Turkish population.

@article{Canbay2013IncreasedGC,
  title={Increased gastric cancer risk with PTEN IVS4 polymorphism in a Turkish population.},
  author={Emel Canbay and Ozlem Timirci Kahraman and Dursun Buğra and Burcu Caykara and Mehmet Fatih Seyhan and Turker Bulut and Sumer Yamaner and Oğuz Ozturk},
  journal={Genetic testing and molecular biomarkers},
  year={2013},
  volume={17 3},
  pages={249-53}
}
We aimed to investigate the association of the phosphatase and tensin homolog (PTEN) IVS4 polymorphism with a gastric cancer (GC) risk in the Turkish population. A hospital-based case-control study was conducted in 93 patients with GC, and 113 healthy controls. The PTEN IVS4 (rs no: 3830675) polymorphism was determined by using polymerase chain reaction-restriction fragment length polymorphism analysis. The PTEN IVS4 (-/-) genotype exhibited a significantly elevated risk for GC compared to… CONTINUE READING

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