Increased frequency of follicular helper T cells in patients with autoimmune thyroid disease.

@article{Zhu2012IncreasedFO,
  title={Increased frequency of follicular helper T cells in patients with autoimmune thyroid disease.},
  author={Chenlu Zhu and Jie Ma and Yingzhao Liu and Jia Tong and Jie Tian and Jianguo Chen and Xinyi Tang and Huaxi Xu and Liwei Lu and Shengjun Wang},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2012},
  volume={97 3},
  pages={
          943-50
        }
}
CONTEXT Follicular helper T (Tfh) cells exert an important role in the autoimmune diseases. AIM Our study aimed to explore the role of Tfh cells in patients with autoimmune thyroid disease (AITD). DESIGN Tfh cell is a new subset regulating the antibody production of B cell. Previous studies implicated CD4+CXCR5+ICOShigh or CD4+CXCR5+PD-1high as the markers of circulating Tfh cells. Sixty-five patients with AITD and 30 healthy controls were enrolled in the current study. The percentages of… CONTINUE READING

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