Increased flow precedes remote arteriolar dilations for some microapplied agonists.

@article{Frame2000IncreasedFP,
  title={Increased flow precedes remote arteriolar dilations for some microapplied agonists.},
  author={M. D. Frame},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2000},
  volume={278 4},
  pages={
          H1186-95
        }
}
  • M. D. Frame
  • Published 2000
  • Chemistry, Medicine
  • American journal of physiology. Heart and circulatory physiology
This study asks which occurs first in time for remote responses: a dilation or a remote change in flow. Arteriolar diameter (approximately 20 microm) and fluorescently labeled red blood cell (RBC) velocity were measured in the cremaster muscle of anesthetized (pentobarbital sodium, 70 mg/kg) hamsters (n = 51). Arterioles were locally stimulated for 60 s with micropipette-applied 10 microg/ml LM-609 (alpha(v)beta(3)-integrin agonist), 10(-3) M adenosine, or 10(-3) M 3-morpholinosydnonimine (SIN… Expand
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