Increased fibrinolytic activity during use of oral contraceptives is counteracted by an enhanced factor XI-independent down regulation of fibrinolysis: a randomized cross-over study of two low-dose oral contraceptives.

@article{Meijers2000IncreasedFA,
  title={Increased fibrinolytic activity during use of oral contraceptives is counteracted by an enhanced factor XI-independent down regulation of fibrinolysis: a randomized cross-over study of two low-dose oral contraceptives.},
  author={Joost Meijers and Saskia Middeldorp and Winnie L Tekelenburg and Abraham E van den Ende and Guido Tans and Martin H. Prins and Jan Rosing and Harry Roger B{\"u}ller and Bonno N. Bouma},
  journal={Thrombosis and haemostasis},
  year={2000},
  volume={84 1},
  pages={9-14}
}
The effect of oral contraceptives (OC) on fibrinolytic parameters was investigated in a cycle-controlled cross-over study in which 28 non-OC using women were randomly prescribed either a representative of the so-called second (30 microg ethinylestradiol, 150 microg levonorgestrel) or third generation OC (30 microg ethinylestradiol, 150 microg desogestrel) and who switched OC after a two month wash out period. During the use of OC, the levels of tissue-type plasminogen activator (tPA) activity… CONTINUE READING

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