Increased extracellular volume and altered mechanics are associated with LVH in hypertensive heart disease, not hypertension alone.

@article{Kuruvilla2015IncreasedEV,
  title={Increased extracellular volume and altered mechanics are associated with LVH in hypertensive heart disease, not hypertension alone.},
  author={Sujith Kuruvilla and Rajesh Janardhanan and Patrick F. Antkowiak and Ellen C. Keeley and Nebiyu Adenaw and Jeremy Brooks and F. H. Epstein and C. M. Kramer and Michael Salerno},
  journal={JACC. Cardiovascular imaging},
  year={2015},
  volume={8 2},
  pages={172-80}
}
OBJECTIVES The goal of this study was to assess the relationship among extracellular volume (ECV), native T1, and systolic strain in hypertensive patients with left ventricular hypertrophy (HTN LVH), hypertensive patients without LVH (HTN non-LVH), and normotensive controls. BACKGROUND Diffuse myocardial fibrosis in HTN LVH patients, as reflected by increased ECV and native T1, may be an underlying mechanism contributing to increased cardiovascular risk compared with HTN non-LVH subjects and… CONTINUE READING