Increased extracellular collagen matrix in myocardial sleeves of pulmonary veins: an additional mechanism facilitating repetitive rapid activities in chronic pacing-induced sustained atrial fibrillation.

@article{Chiu2005IncreasedEC,
  title={Increased extracellular collagen matrix in myocardial sleeves of pulmonary veins: an additional mechanism facilitating repetitive rapid activities in chronic pacing-induced sustained atrial fibrillation.},
  author={Yung-Tsung Chiu and T J Wu and H Wei and Ching-Chang Cheng and Nai-Nu Lin and Y Chen and C L Ting},
  journal={Journal of cardiovascular electrophysiology},
  year={2005},
  volume={16 7},
  pages={753-9}
}
UNLABELLED Increased ECM in canine PVs. INTRODUCTION Cell uncoupling due to fibrosis or increased extracellular collagen matrix (ECM) affects the formation of ectopic focal activity. Whether or not the increase of ECM also exists in the pulmonary veins (PVs) with rapid atrial pacing is unknown. We sought to test the hypothesis that in chronic atrial pacing dogs with sustained atrial fibrillation (AF), the amount of ECM was increased in both atria and the PVs. METHODS AND RESULTS We induced… CONTINUE READING

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Increased extracellular collagen matrix in myocardial sleeves of pulmonary veins : an additional mechanism facilitating repetitive rapid activities in chronic pacing - induced sustained atrial fibrillation .
Increased extracellular collagen matrix in myocardial sleeves of pulmonary veins : an additional mechanism facilitating repetitive rapid activities in chronic pacing - induced sustained atrial fibrillation .
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