Increased expression of the Hsp70 cochaperone HspBP1 in tumors.


Hsp70 levels are elevated in a number of different tumors. The Hsp70 cochaperone heat shock protein-binding protein 1 (HspBP1) has been shown to bind to Hsp70, inhibit its activity and promote dissociation of nucleotide from the Hsp70 ATPase domain. The purpose of this study was to determine if the levels of HspBP1 are altered in tumor cells. In this report… (More)


Cite this paper

@article{Raynes2003IncreasedEO, title={Increased expression of the Hsp70 cochaperone HspBP1 in tumors.}, author={Deborah A. Raynes and Michael W Graner and Rochelle Bagatell and Catherine A McLellan and Vince Guerriero}, journal={Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine}, year={2003}, volume={24 6}, pages={281-5} }