Increased expression of stem cell markers in malignant melanoma

@article{Klein2007IncreasedEO,
  title={Increased expression of stem cell markers in malignant melanoma},
  author={Walter M. Klein and Bryan P Wu and Shuping Zhao and Hong Wu and Andr{\'e}s J. P. Klein-Szanto and Steven R. Tahan},
  journal={Modern Pathology},
  year={2007},
  volume={20},
  pages={102-107}
}
The potential role of stem cells in neoplasia is a subject of recent interest. Three markers of melanocytic stem cells have been described recently. CD166 is expressed on the surface of mesenchymal stem cells and has been found on human melanoma cell lines. CD133 is expressed on the surface of dermal-derived stem cells that are capable of differentiating into neural cells. Nestin is an intermediate filament expressed in the cytoplasm of neuroepithelial stem cells. In this study, we evaluate the… CONTINUE READING

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