Increased expression of pAKT is associated with radiation resistance in cervical cancer

@article{Kim2006IncreasedEO,
  title={Increased expression of pAKT is associated with radiation resistance in cervical cancer},
  author={T-J Kim and J E Lee and Seung-Hun Song and J-J Choi and Chel Hun Choi and B G Kim and J R Lee and D S Bae},
  journal={British Journal of Cancer},
  year={2006},
  volume={94},
  pages={1678 - 1682}
}
Phosphorylated AKT (pAKT) is a major contributor to radioresistance in human cancers. The aim of this study was to investigate the association of pAKT expression and radiation resistance in cervical cancer. A retrospective review was made of the records of 27 women who received primary radiation therapy due to locally advanced cervical cancer (LACC) with FIGO stage IIB–IVA. Nine patients regarded as radiation resistant developed local recurrences with a median progression free interval of 9… CONTINUE READING