Increased expression of nitric oxide synthase and dendritic injury in simian immunodeficiency virus encephalitis.

@article{Li1999IncreasedEO,
  title={Increased expression of nitric oxide synthase and dendritic injury in simian immunodeficiency virus encephalitis.},
  author={Qing Li and Lee E. Eiden and Winston P Cavert and Todd A. Reinhart and Dianne M. Rausch and Elisabeth A Murray and Eberhard Weihe and Ashley T Haase},
  journal={Journal of human virology},
  year={1999},
  volume={2 3},
  pages={139-45}
}
OBJECTIVES Widespread dendritic injury may be one mechanism involved in the neurologic impairment that occurs in HIV-1 infection. The objectives of this study were to quantitate the extent of dendritic injury in a primate model of central nervous system (CNS) infection, investigate the role of nitric oxide (NO) as a mediator of neuropathologic changes, and evaluate the relation of these changes to cognitive and motor function. STUDY DESIGN/METHODS Cognitive and motor function was assessed in… CONTINUE READING
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