Increased expression of neutral endopeptidase (NEP) and aminopeptidase N (APN) on peripheral blood mononuclear cells in patients with multiple sclerosis.

@article{Ziaber2000IncreasedEO,
  title={Increased expression of neutral endopeptidase (NEP) and aminopeptidase N (APN) on peripheral blood mononuclear cells in patients with multiple sclerosis.},
  author={J Ziaber and Zbigniew Baj and Jaroslaw Pasnik and Henryk Mokołaj Chmielewski and Henryk Tch{\'o}rzewski},
  journal={Immunology letters},
  year={2000},
  volume={71 2},
  pages={127-9}
}
We studied CD10 Ag of neutral endopeptidase (NEP) and CD13 Ag of aminopeptidase N (APN) expression on peripheral blood mononuclear cells (PBMC) as cells activation markers and for their transendothelial migration properties in three groups of MS patients (total 58); with acute exacerbation of MS (n = 18), primary progressive MS (n = 17) and with MS remission (n = 23). The control group (OND) consisted of 24 patients, suffering from other noninflammatory neurological diseases. CD10 Ag and CD13… CONTINUE READING