Increased expression of mineralocorticoid receptor in human ileum after total colectomy: immunohistochemical and immunoblotting studies.

@article{Fukushima1994IncreasedEO,
  title={Increased expression of mineralocorticoid receptor in human ileum after total colectomy: immunohistochemical and immunoblotting studies.},
  author={Kikuro Fukushima and Hironobu Sasano and Iwao Sasaki and Hiroshi Nagura and Yuji Funayama and Seiki Matsuno},
  journal={The Tohoku journal of experimental medicine},
  year={1994},
  volume={173 4},
  pages={383-90}
}
Aldosterone is known to regulate transmembrane ion transport and water absorption through its binding to mineralocorticoid receptor (MR) in the mammalian colon. A possible roles of aldosterone has been suggested in increased water absorption from remnant ileum in the patients with total colectomy. We, therefore, studied immunolocalization of MR in remnant ileal mucosa in the patients with total colectomy in order to study the role of aldosterone in water and sodium absorption in these patients… CONTINUE READING