Increased expression of microRNA-9 predicts an unfavorable prognosis in human glioma

  title={Increased expression of microRNA-9 predicts an unfavorable prognosis in human glioma},
  author={Zhenyu Wu and Liang Wang and Gang Li and Hui Liu and Feiyan Fan and Zhaobo Li and Yunqing Li and Guodong Gao},
  journal={Molecular and Cellular Biochemistry},
microRNA-9 (miR-9) has been found to be upregulated along with tumor progression of gliomas by microarray-based expression profiling, and also be strongly linked to glioblastoma subtypes. However, its prognostic value in glioma is still elusive. miR-9 expression in human gliomas and nonneoplastic brain tissues was measured by real-time quantitative RT-PCR assay. miR-9 expression in glioma tissues was significantly higher than that in corresponding nonneoplastic brain tissues (P < 0.001). The… CONTINUE READING
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