Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma.

@article{Yoshizaki1997IncreasedEO,
  title={Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma.},
  author={Tomokazu Yoshizaki and Hiroshi Sato and Yuichiro Maruyama and Shigeyuki Murono and Mitsuru Furukawa and Chan Soon Park and Motoharu Seiki},
  journal={Cancer},
  year={1997},
  volume={79 1},
  pages={139-44}
}
BACKGROUND Three types of membrane type-matrix metalloproteinases (MT-MMPs) have been identified as activators of pro-MMP2 (gelatinase A/72-kilodalton Type IV collagenase), which is believed to be crucial for tumor invasion and metastasis. MT1-MMP has been shown to be widely expressed in various tissues and to be overexpressed in lung and gastric carcinomas. METHODS Activation of pro-MMP2 was examined in head and neck squamous cell carcinoma (HNSCC) by gelatin zymography. The expression of… CONTINUE READING
48 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Similar Papers

Loading similar papers…