Increased expression of magnocellular arginine vasopressin mRNA in paraventricular nucleus of stress-induced depression-model rats.

@article{Nakase1998IncreasedEO,
  title={Increased expression of magnocellular arginine vasopressin mRNA in paraventricular nucleus of stress-induced depression-model rats.},
  author={Shinji Nakase and Isao Kitayama and Hideaki Soya and K Hamanaka and Jun Nomura},
  journal={Life sciences},
  year={1998},
  volume={63 1},
  pages={23-31}
}
Exposure of rats to long-term intermittent walking stress results in a persistent inactive behavior in the subsequent two weeks in about 50% of rats (depression-model rats) while the activity returns gradually toward baseline in other rats (spontaneous recovery rats). To explore the role of hypothalamic-pituitary-adrenal (HPA) axis in these depression-model rats, we examined changes in the gene expression of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) in the… CONTINUE READING