Increased expression of inducible HSP70 in apoptotic cells is correlated with their efficacy for antitumor vaccine therapy.

@article{Mass2004IncreasedEO,
  title={Increased expression of inducible HSP70 in apoptotic cells is correlated with their efficacy for antitumor vaccine therapy.},
  author={Delphine Mass{\'e} and Fr{\'e}d{\'e}ric Ebstein and Gwenola Bougras and Jean Harb and Khaled Meflah and Marc Gr{\'e}goire},
  journal={International journal of cancer},
  year={2004},
  volume={111 4},
  pages={
          575-83
        }
}
Apoptosis is a physiologic process in normal development, tissue remodeling and cell turnover. This cell death is noninflammatory and nonimmunogenic, but when associated with a danger signal, it can activate the immune system. However, the capacity of apoptotic cells to activate the immune system is not clearly established, although dead tumor cells have been largely exploited as a source of TAA in cellular therapy against cancer. From these cellular preparations, contradictory results have… CONTINUE READING

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