Increased expression of hypoxia-inducible factor-1alpha and Bcl-2 in varicocele and varicose veins.

Abstract

BACKGROUND Primary vein wall abnormalities leading to secondary blood stasis and increased venous pressure that cause tissue hypoxia are observed in varicocele and varicose veins. Both types of diseased vessels are characterized by dilated thickened vein walls. Hypoxia upregulates Bcl-2 (antiapoptosis protein) expression in different human cell types. We… (More)
DOI: 10.1016/j.avsg.2011.12.014

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@article{Lee2012IncreasedEO, title={Increased expression of hypoxia-inducible factor-1alpha and Bcl-2 in varicocele and varicose veins.}, author={Jane-Dar Lee and Wen-Kai Yang and Tsung-Han Lee}, journal={Annals of vascular surgery}, year={2012}, volume={26 8}, pages={1100-5} }