Increased expression of hypoxia-inducible factor 1α in type I and type II endometrial carcinomas

@article{Pansare2007IncreasedEO,
  title={Increased expression of hypoxia-inducible factor 1α in type I and type II endometrial carcinomas},
  author={Vaishali Pansare and Adnan R. Munkarah and Veronica L Schimp and M. Arabi and Ghassan M. Saed and Robert J. T. Morris and Rouba Ali-Fehmi},
  journal={Modern Pathology},
  year={2007},
  volume={20},
  pages={35-43}
}
Hypoxia-inducible factor 1α (HIF-1α) is a nuclear protein that is upregulated in many tumors and triggers biologic events intimately associated with aggressive tumor behavior. The aim of this study was to analyze the expression of HIF-1α, vascular endothelial growth factor (VEGF), Ki-67 and p53 in type I and type II endometrial adenocarcinoma. In total, 149 patients diagnosed with endometrial adenocarcinoma in our institute from 1995 to 2001 were included in this study, of which 108 were type I… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 29 references

The effect of cyclooxygenase-2 expression on tumor vascularity in advanced stage ovarian serous carcinoma

MC Rouba Ali-Fehmi, I Khalifeh, JM Malone
Cancer 2003;98:1423–1429 • 2003

Coexpression of hypoxia - inducible factors 1 a and 2 a , carbonic an - hydarse IX , and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survi

EP Hui, A Chan, F Pezella
Clin Cancer Res • 2002

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