Increased expression of galectin-1 is associated with human oral squamous cell carcinoma development.

@article{Ding2009IncreasedEO,
  title={Increased expression of galectin-1 is associated with human oral squamous cell carcinoma development.},
  author={Y Ding and Ji-hua Dong and Li-li Chen and Han-Dong Zhang},
  journal={Oncology reports},
  year={2009},
  volume={21 4},
  pages={983-7}
}
Galectin-1 (Gal-1) is a newly found immunoregulatory carbohydrate-binding protein in cancer biology. The purpose of this study was to evaluate the effects of Gal-1 on oral squamous cell carcinoma (OSCC) development. Immunohistochemistry, Western blotting and RT-PCR were carried out in 62 primary OSCC, 38 oral leukoplakia (OPL) tissues to detect the Gal-1 expression in both protein and mRNA levels. Ten normal oral mucosa (NOM) tissues were used as control. Gal-1 protein was significantly… CONTINUE READING

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