Increased expression of estrogen receptor alpha and beta in the nucleus basalis of Meynert in Alzheimer's disease.

Abstract

The human nucleus basalis of Meynert (NBM) is severely affected in Alzheimer's disease (AD). Since estrogens may reduce both the risk and severity of AD, possibly by an action on the cholinergic system, we determined whether estrogen receptors are present in the human NBM and what their changes are in normal aging and in AD. ERalpha was expressed to a… (More)

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@article{Ishunina2001IncreasedEO, title={Increased expression of estrogen receptor alpha and beta in the nucleus basalis of Meynert in Alzheimer's disease.}, author={Tatjana A Ishunina and D. F. Swaab}, journal={Neurobiology of aging}, year={2001}, volume={22 3}, pages={417-26} }