Increased expression of caspase 2 in experimental and human temporal lobe epilepsy

@article{Narkilahti2007IncreasedEO,
  title={Increased expression of caspase 2 in experimental and human temporal lobe epilepsy},
  author={Susanna Narkilahti and Leena Jutila and Irina Alafuzoff and Kari O Karkola and Leo Palj{\"a}rvi and A. S. T. Immonen and Matti Vapalahti and Esa Mervaala and Reetta K{\"a}lvi{\"a}inen and Asla Pitk{\"a}nen},
  journal={NeuroMolecular Medicine},
  year={2007},
  volume={9},
  pages={129-144}
}
Temporal lobe epilepsy (TLE) is often caused by a neurodegenerative brain insult that triggers epileptogenesis, and eventually results in spontaneous seizures, i.e., epilepsy. Understanding the mechanisms of cell death is a key for designing new drug therapies for preventing the neurodegeneration associated with TLE. Here, we investigated the expression of caspase 2, a protein involved in programmed cell death, during the course of epilepsy. We investigated caspase 2 expression in hippocampal… CONTINUE READING

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