Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients.

@article{Lomnytska2006IncreasedEO,
  title={Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients.},
  author={Marta Lomnytska and Anna Dubrovska and Ulf Hellman and Natalya Volodko and Serhiy Souchelnytskyi},
  journal={International journal of cancer},
  year={2006},
  volume={118 2},
  pages={412-21}
}
Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer using 2-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization time of flight mass spectrometry. Truncated forms of cytosolic serine hydroxymethyl transferase (cSHMT), T-box transcription factor 3 (Tbx3) and utrophin were aberrantly expressed in samples from cancer patients as compared to samples from noncancerous cases. Aberrant expression of proteins was validated by… CONTINUE READING
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