Increased expression of Gem after rat sciatic nerve injury

  title={Increased expression of Gem after rat sciatic nerve injury},
  author={Youhua Wang and Xinghai Cheng and Zhengming Zhou and Hao Wu and Long Long and Xingxing Gu and Guangfei Xu},
  journal={Journal of Molecular Histology},
Gem belongs to the Rad/Gem/Kir subfamily of Ras-related GTPases, whose expression is induced in several cell types upon activation by extracellular stimuli. Two functions of Gem have been demonstrated, including regulation of voltage-gated calcium channel activity and inhibition of Rho kinase-mediated cytoskeletal reorganization, such as stress fiber formation and neurite retraction. Because of the essential relationship between actin reorganization and peripheral nerve regeneration, we… CONTINUE READING
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