Increased expression of CD200 on circulating CD11b+ monocytes in patients with neovascular age-related macular degeneration.

@article{Singh2013IncreasedEO,
  title={Increased expression of CD200 on circulating CD11b+ monocytes in patients with neovascular age-related macular degeneration.},
  author={Amardeep Singh and Mads Kr{\"u}ger Falk and Thomas Vauvert F Hviid and Torben Lykke S{\o}rensen},
  journal={Ophthalmology},
  year={2013},
  volume={120 5},
  pages={
          1029-37
        }
}
  • Amardeep Singh, Mads Krüger Falk, +1 author Torben Lykke Sørensen
  • Published in Ophthalmology 2013
  • Medicine
  • OBJECTIVE Dysregulation of retinal microglial activity has been implicated in the pathogenesis of neovascular age-related macular degeneration. Microglia activity can be regulated through the membrane protein CD200 and its corresponding receptor, the CD200 receptor (CD200R). Because both the ligand and the receptor are expressed on a broad spectrum of cell types, we set out to study the expression of CD200 and CD200R on CD11b+ monocytes, granulocytes, and subsets of T lymphocytes. DESIGN… CONTINUE READING

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