Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats.

@article{Larivire1993IncreasedEC,
  title={Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats.},
  author={Roxanne C Larivi{\`e}re and Ga{\'e}tan Thibault and Ernesto L Schiffrin},
  journal={Hypertension},
  year={1993},
  volume={21 3},
  pages={
          294-300
        }
}
Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide produced in the endothelium of blood vessels that may play an important role in the control of local blood flow and could be involved in the pathogenesis of hypertension. We investigated immunoreactive ET-1 (ir-ET-1) levels in acid extracts from blood vessels of deoxycorticosterone acetate (DOCA)-salt and spontaneously hypertensive rats. We found that segments of thoracic aorta and the mesenteric vascular bed contain significantly more… CONTINUE READING

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Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor

G De Nucci, R Thomas, +4 authors JR Vane
  • Proc NatlAcad Sci USA
  • 1988
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

: Relation with structural changes

A Chobanian
  • 1992