Increased effector-target cell conjugate formation due to HLA restricted specific antigen recognition.

@article{Voss2009IncreasedEC,
  title={Increased effector-target cell conjugate formation due to HLA restricted specific antigen recognition.},
  author={Ching Y. Voss and Sara Deola and Thomas A. Fleisher and Francesco M. Marincola},
  journal={Immunologic research},
  year={2009},
  volume={45 1},
  pages={13-24}
}
The T cell receptor (TCR) orchestrates T cell mediated-cytotoxicity through a complex interaction that results in an antigen-specific effector-target cell conjugate formation. While it is well recognized that specific TCR/antigen interactions generate the immunological synapse, their direct contribution to the effector-target cell conjugate has not been… CONTINUE READING