Increased dynorphin immunoreactivity in spinal cord after traumatic injury.

Abstract

Opiate antagonists, at high doses, have been shown to improve physiological variables and outcome after experimental spinal injury. Dynorphin appears to be unique amongst opioids in producing hindlimb paralysis after intrathecal injection. Taken together, these findings suggest a possible pathophysiological role for endogenous opioids, particularly… (More)

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@article{Faden1985IncreasedDI, title={Increased dynorphin immunoreactivity in spinal cord after traumatic injury.}, author={Alan I. Faden and Christopher J. Molineaux and John G. Rosenberger and Thomas P. Jacobs and Brian M. Cox}, journal={Regulatory peptides}, year={1985}, volume={11 1}, pages={35-41} }