Increased detection rate of human papillomavirus in cervical scrapes by the polymerase chain reaction as compared to modified FISH and southern-blot analysis.

@article{Melchers1989IncreasedDR,
  title={Increased detection rate of human papillomavirus in cervical scrapes by the polymerase chain reaction as compared to modified FISH and southern-blot analysis.},
  author={Willem J G Melchers and A.J.C. Van Den Brule and Jan M. M. Walboomers and Martijn de Bruin and Marion Burger and Paul Herbrink and Chris J L M Meijer and Jan Lindeman and Wim G. V. Quint},
  journal={Journal of medical virology},
  year={1989},
  volume={27 4},
  pages={329-35}
}
Cervical scrapes from 80 women with a positive cytology result were tested for the presence of human papillomavirus (HPV) using the polymerase chain reaction (PCR) and compared to the results obtained with the modified filter in situ hybridisation (FISH) and the Southern-blot techniques. The sensitivity of the modified FISH and the Southern-blot was similar, and HPV was detected in 46% of the patients. The sensitivity of the PCR appeared to be higher, and HPV was detected in 70% of the patients… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
30 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 30 extracted citations

Similar Papers

Loading similar papers…