Increased detection of rickettsialpox in a New York City hospital following the anthrax outbreak of 2001: use of immunohistochemistry for the rapid confirmation of cases in an era of bioterrorism.

@article{Koss2003IncreasedDO,
  title={Increased detection of rickettsialpox in a New York City hospital following the anthrax outbreak of 2001: use of immunohistochemistry for the rapid confirmation of cases in an era of bioterrorism.},
  author={Tamara Koss and Eric L. Carter and Marc E. Grossman and David N. Silvers and Asher D. Rabinowitz and Joseph Singleton and Sherif R Zaki and Christopher D. Paddock},
  journal={Archives of dermatology},
  year={2003},
  volume={139 12},
  pages={
          1545-52
        }
}
BACKGROUND Rickettsialpox is a self-limited febrile illness with skin lesions that may be mistaken for signs of potentially more serious diseases, such as cutaneous anthrax or chickenpox. The cluster of cutaneous anthrax cases from bioterrorism in October 2001 likely heightened awareness of and concern for cutaneous eschars. OBJECTIVES To apply an immunohistochemical technique on paraffin-embedded skin biopsy specimens for diagnosing rickettsialpox, and to compare the reported incidence of… 
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