Increased density of GAD65/67 immunoreactive neurons in the posterior subiculum and parahippocampal gyrus in treated patients with chronic schizophrenia.

Abstract

OBJECTIVES Alterations of glutamic acid decarboxylase (GAD) play a crucial role in schizophrenic pathology. While GAD has been studied in several brain regions, its expression in the posterior hippocampus formation has not been investigated in schizophrenia. METHODS We studied the brains of 17 patients with chronic schizophrenia and 15 controls. Using the… (More)
DOI: 10.3109/15622975.2010.539270

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