Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia.

@article{Dglise2005IncreasedCE,
  title={Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia.},
  author={S{\'e}bastien D{\'e}glise and David Martin and Herv{\'e} Probst and François Saucy and Daniel Hayoz and G{\'e}rard Waeber and Pascal Nicod and H B Ris and Jean-Marc Corpataux and J. A. Haefliger},
  journal={Journal of vascular surgery},
  year={2005},
  volume={41 6},
  pages={1043-52}
}
OBJECTIVE Intimal hyperplasia is a vascular remodelling process that occurs after a vascular injury. The mechanisms involved in intimal hyperplasia are proliferation, dedifferentiation, and migration of medial smooth muscle cells towards the subintimal space. We postulated that gap junctions, which coordinate physiologic processes such as cell growth and differentiation, might participate in the development of intimal hyperplasia. Connexin43 (Cx43) expression levels may be altered in intimal… CONTINUE READING

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