Increased concentrations of transforming growth factor beta1 and beta2 in the plasma of patients with glioblastoma.

@article{Schneider2006IncreasedCO,
  title={Increased concentrations of transforming growth factor beta1 and beta2 in the plasma of patients with glioblastoma.},
  author={Thomas Schneider and Michael Sailer and Siegfried Ansorge and Raimund Firsching and Dirk Reinhold},
  journal={Journal of neuro-oncology},
  year={2006},
  volume={79 1},
  pages={61-5}
}
Recently, several in vitro studies have demonstrated production of the potent immunosuppressive cytokine transforming growth factor beta (TGF-beta)2 in glioblastoma cell lines. Systematic studies of the concentration of TGF-beta isoforms in the plasma of patients harboring intracerebral tumors do not exist. In the present study, the concentrations of TGF-beta1 and TGF-beta2 in platelet-poor plasma of 21 patients with glioblastoma before and after extensive resection were measured by specific… CONTINUE READING

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