Increased circulating cytokines in patients with myocarditis and cardiomyopathy.

  title={Increased circulating cytokines in patients with myocarditis and cardiomyopathy.},
  author={Akira Matsumori and Takashi Yamada and Hiroshi Suzuki and Yoshika Matoba and Shigetake Sasayama},
  journal={British heart journal},
  volume={72 6},
OBJECTIVES To elucidate the potential role of cytokines in the pathogenesis of cardiomyopathy and myocarditis. BACKGROUND Experimental studies show that certain cytokines depress myocardial contractility and that tumour necrosis factor-alpha plays an important part in the pathogenesis of myocardial injury in animal models of viral and autoimmune myocarditis. METHODS Plasma interleukin 1-alpha, interleukin 1-beta, interleukin-2, interleukin-6, tumour necrosis factor-alpha, tumour necrosis… CONTINUE READING