Increased circulating and intrahepatic T-cell-specific chemokines in chronic hepatitis C: relationship with the type of virological response to peginterferon plus ribavirin combination therapy.

@article{Apolinario2004IncreasedCA,
  title={Increased circulating and intrahepatic T-cell-specific chemokines in chronic hepatitis C: relationship with the type of virological response to peginterferon plus ribavirin combination therapy.},
  author={Arantxa Apolinario and Mois{\'e}s Diago and Oreste Lo Iacono and Raquel Lorente and Celia Patricia Perez and Pedro Lorenzo Majano and Gerardo Clemente and Carmelo Garc{\'i}a-Monz{\'o}n},
  journal={Alimentary pharmacology & therapeutics},
  year={2004},
  volume={19 5},
  pages={551-62}
}
AIMS To determine the serum and intrahepatic levels of T-helper-1-associated chemokines in patients with chronic hepatitis C before, during and after peginterferon plus ribavirin combination therapy and to search for correlations with baseline characteristics of hepatitis C virus-related chronic liver disease and type of therapeutic response. METHODS Serum chemokine levels were determined by enzyme-linked immunosorbent assays and intrahepatic chemokine messenger RNA and protein levels were… CONTINUE READING