Increased cholinergic antagonism underlies impaired beta-adrenergic response in ovalbumin-sensitized guinea pigs.

Abstract

The goal of this study was to determine if the hyporesponsiveness to beta-adrenoceptor stimulation observed in ovalbumin-sensitized tracheal smooth muscle is due to increased cholinergic muscarinic tone or to a defect in the beta-adrenergic cascade itself. We examined the effects of ovalbumin-sensitization on the responsiveness of guinea pig tracheae to… (More)

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Cite this paper

@article{WillsKarp1993IncreasedCA, title={Increased cholinergic antagonism underlies impaired beta-adrenergic response in ovalbumin-sensitized guinea pigs.}, author={Marsha Wills-Karp and Mhairi Gilmour}, journal={Journal of applied physiology}, year={1993}, volume={74 6}, pages={2729-35} }