Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

Abstract

The discovery that heterozygous missense mutations in the gene encoding triggering receptor expressed on myeloid cells 2 (TREM2) are risk factors for Alzheimer’s disease (AD), with only the apolipoprotein E (APOE) ε4 gene allele conferring a higher risk, has led to increased interest in immune biology in the brain. TREM2 is expressed on microglia, the… (More)
DOI: 10.1186/s13024-016-0071-x

Topics

2 Figures and Tables

Statistics

05010020162017
Citations per Year

Citation Velocity: 41

Averaging 41 citations per year over the last 2 years.

Learn more about how we calculate this metric in our FAQ.

Slides referencing similar topics