Increased cerebral infarction by cyclic flow reductions: studies in the guinea pig MCA thrombosis model.

@article{Kawano1998IncreasedCI,
  title={Increased cerebral infarction by cyclic flow reductions: studies in the guinea pig MCA thrombosis model.},
  author={K I Kawano and Yasuhiko Ikeda and Kazunao Kondo and Kazuo Umemura},
  journal={The American journal of physiology},
  year={1998},
  volume={275 5 Pt 2},
  pages={R1578-83}
}
We have developed a photochemical model of thrombotic middle cerebral artery (MCA) occlusion in the guinea pig for investigating factors contributing to the development of cerebral infarction. In this model, cyclic flow reductions (CFRs) after recanalization of the MCA are a common observation and might contribute to the development of cerebral infarction. Therefore, we sought to measure the time course of recanalization of the guinea pig MCA after the artery had been occluded by a thrombus… CONTINUE READING

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